Curriculum Vitae

Laise DE MORAES

CONTACT DETAILS
Office address
Laboratório de Medicina e Saúde Pública (MeSP²)
Instituto Gonçalo Moniz / Fundação Oswaldo Cruz
Rua Waldemar Falcão 121, Candeal, Salvador-BA, 40276-710 BR
TEL.
Office: 55-71-3176-2279 / Mobile: 55-71-98689-6854
E-mail
laise.moraes@fiocruz.br
ORCID
https://orcid.org/0000-0001-9095-5860
RESEARCH POSITION
2024 – present
Instituto Gonçalo Moniz / Fundação Oswaldo Cruz (Brazil) Postdoctoral Research Assistant
(CONTINUOS) EDUCATION
2026 – present
Universidade Federal da Bahia (Brazil) BSc in Statistics
2018 – 2024
Universidade Federal da Bahia (Brazil) PhD in Health Sciences
2015 – 2017
Universidade Federal da Bahia (Brazil) MSc in Health Sciences
2010 – 2014
Escola Bahiana de Medicina e Saúde Pública (Brazil) BSc in Biomedicine
AWARDS AND HONORS
05 Dec 2025
Universidade Federal da Bahia (Brazil) Winner of the UFBA Award: Doctoral Theses, Master's Dissertations and Final Papers 2024 Prêmio UFBA: Teses, Dissertações e Trabalhos de Conclusão 2024
04 Dec 2020
Instituto Gonçalo Moniz / Fundação Oswaldo Cruz (Brazil) Dedication Award in the COVID-19 Molecular Diagnostics Platform Desempenho e Dedicação na Plataforma de Diagnóstico Molecular COVID-19
TEACHING EXPERIENCE
Nov 2025 – present
PGPAT, Universidade Federal da Bahia (Brazil) Science and Data Visualization in Healthcare Programa de Pós-graduação em Patologia Humana, Ciência e Visualização de Dados em Saúde
Apr 2025 – Jun 2025
PMBqBM, Universidade Federal da Bahia (Brazil) Bioinformatics Programa Multicêntrico de Pós-graduação em Bioquímica e Biologia Molecular, Bioinformática
Oct 2024 – present
PgBSMI, Instituto Gonçalo Moniz / Fundação Oswaldo Cruz (Brazil) Introduction to Bioinformatics Programa de Pós-graduação em Biotecnologia em Saúde e Medicina Investigativa, Fundamentos em Bioinformática
RESEARCH TRAINING / SUPERVISION AND TUTORING
2026 – present
PPgCS, Universidade Federal da Bahia (Brazil) PhD Co-supervisor: Thayná Torres Gonzalez
Apr 2025 – Jun 2025
PPgCS, Universidade Federal da Bahia (Brazil) MSc Co-supervisor: Sara de Medina Batista Pimentel
2022
Escola Bahiana de Medicina e Saúde Pública (Brazil) BSc Supervisor: Joyce Karoline da Silva
2021
Escola Bahiana de Medicina e Saúde Pública (Brazil) BSc Supervisor: Laísia Falcão Alonso Uzêda
2020
Escola Bahiana de Medicina e Saúde Pública (Brazil) BSc Supervisor: Ágatha Sales Morais
2019
Escola Bahiana de Medicina e Saúde Pública (Brazil) BSc Supervisor: Ítala Hauanne Araújo Silva
PUBLICATIONS (ARTICLES IN PEER-REVIEWED JOURNALS)
  1. 33.Shuab G, de Oliveira C, dos Santos CC, de Moraes L, dos Santos CD, Nunes DS, Moura JCP, Naveca FG, de Bycker-Nogueira F, de Filippis AMB, Giovanetti M. Retrospective and Contemporary Genomic Surveillance Reveals Genotype-Specific Dengue Lineage Dynamics in Rio de Janeiro. Viruses. 2026;18(10):1070. doi:10.3390/v18101070.
  2. 32.Khouri R, Silva-Santos G, de Moraes L, Amorim Santos L, Menezes SM, Sanson D, et al. Modeling of ex vivo immune response reveals a central role for CD8+CD25+ cells in Adult T-cell Leukemia survival: a long-term prospective cohort study. Tumour Virus Res. 2026 Aug 26;22:200349. doi: 10.1016/j.tvr.2026.200349.
  3. 31.Santos LA, Castillo A, Gustani-Buss E, Hitchings MDT, Liu P, Iovine N, Cash MN, Estrada JL, de Moraes L, et al. Genomic Diversity of Human Respiratory Syncytial Virus (HRSV) Type A in a Pediatric Cohort in the United States After the Onset of the COVID-19 Pandemic. Microorganisms. 2026 Jul 29;14(8):1656. doi: 10.3390/microorganisms14081656.
  4. 30.Cerqueira-Silva T, de Moraes L, Pereira BJ, Silva J, Orge C, Akrami K, et al. Early transcriptional signature in chikungunya predicts chronic arthralgia and reveals deficient antiviral response. J Infect Dis. 2026 Jul 21:jiag366. doi: 10.1093/infdis/jiag366.
  5. 29.Wang W-K, Netto EM, Hsieh S-C, Chen G-H, Falcão MB, Pedroso C, Mayoral R, Costa R, Dai Y-C, Salomon RC, Tsai J-J, de Moraes L, et al. Identification of multiple arbovirus infections/exposure in Northeastern Brazil using a multiplex microsphere immunoassay. J Clin Microbiol. 2026 Jun 10;64(6):e0001326. doi: 10.1128/jcm.00013-26.
  6. 28.Aguilar Ticona JP, Amorim Santos L, Meng X, Nery N Jr, Fofana MO, de Moraes L, et al. Metagenomic surveillance reveals off-season circulation of respiratory viruses during the COVID-19 pandemic in Salvador, Brazil. New Microbes New Infect. 2026 Feb 6;70:101717. doi: 10.1016/j.nmni.2026.101717.
  7. 27.Lima ACMM, Moraes L, Amorim RL, Cucco MS, Silva RML, Giovanetti M, et al. Cross-platform protocol for HTLV-1 whole-genome sequencing using nanopore and Illumina technologies. Next Res. 2026;3:101110. doi: 10.1016/j.nexres.2025.101110.
  8. 26.Dantas ACS, Oliveira HBM, Pereira TTS, Lima AF, Santos LS, Matos JMF, Aranha T, Magno L, Soares F, Dourado I, Torres TS, Veloso VG, da Costa Ferreira Junior O, de Moraes L, et al. Analysis of the prevalence, spread, and mutation patterns of SARS-CoV-2 variants: data from COVID-19 testing expansion strategy study in Salvador, Northeast Brazil. Sci Rep. 2025 Aug 29;15(1):31866. doi: 10.1038/s41598-025-17691-x.
  9. 25.Polita D, de Moraes L, Giovanetti M, Rego FFA, Carvalho G, Santos LA, et al. South-to-Southeast Expansion of HIV-1 Subtype C in Brazil. J Med Virol. 2025 Sep;97(9):e70580. doi: 10.1002/jmv.70580.
  10. 24.Thompson C, Leal CV, da Silva Faustino R, Leomil L, Jagadeeshwari U, Sharma R, de Oliveira M, Tschoeke D, Felix T, Macedo L, Khouri R, Koolen H, Landuci F, de Rezende C, Strobel Í, de Moraes L, et al. Co-occurrence of SARS-CoV-2 variants in rivers and sewage in India and Brazil. Sci Total Environ. 2025 Jan 1;958:178089. doi: 10.1016/j.scitotenv.2024.178089.
  11. 23.Paz LN, de Moraes L, Santos LA, Hamond C, Pinna MH. Insights into host-pathogen interaction based on the comparison of genomes of leptospira interrogans isolated from dogs, humans, and a rodent in the same epidemiological context: A one health approach. Heliyon. 2024 Dec 26;11(1):e41531. doi: 10.1016/j.heliyon.2024.e41531.
  12. 22.Ferraz H, Akrami K, Moraes L, Gusmão LC, Coelho G, Freitas D, et al. Screening semen samples for Zika virus infection: role for serologic and RT-PCR testing. Front Trop Dis. 2025;5:1489647. doi: 10.3389/fitd.2024.1489647.
  13. 21.Polita D, de Moraes L, Giovanetti M, de Almeida Rego FF, Santos LA, Junqueira DM, et al. Tracing the Dispersal Pathway of HIV-1 Subtype C to Bahia: Phylogenetic Connections to Southern Brazil. Viruses. 2024 Dec 19;16(12):1941. doi: 10.3390/v16121941.
  14. 20.Amorim G, Jaworski J, Yang J, Cordeiro-Santos M, Kritski AL, Figueiredo MC, Turner M, Andrade BB, Velez Edwards DR, Santos AR, Rolla VC, Sterling TR, Haas DW; Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil network. Pharmacogenetics of tuberculosis treatment toxicity and effectiveness in a large Brazilian cohort. Pharmacogenet Genomics. 2025 Feb 1;35(2):55-64. doi: 10.1097/FPC.0000000000000552.
  15. 19.Viana PAB, Tschoeke DA, de Moraes L, Santos LA, Barral-Netto M, Khouri R, et al. Design and implementation of a metagenomic analytical pipeline for respiratory pathogen detection. BMC Res Notes. 2024 Oct 3;17(1):291. doi: 10.1186/s13104-024-06964-9.
  16. 18.Meirelles PM, Viana PAB, Tschoeke DA, de Moraes L, Santos LA, Barral-Netto M, et al. Optimizing next-generation sequencing efficiency in clinical settings: analysis of read length impact on cost and performance. BMC Genomics. 2024 Sep 12;25(1):856. doi: 10.1186/s12864-024-10778-1.
  17. 17.Sagay AS, Hsieh SC, Dai YC, Chang CA, Ogwuche J, Ige OO, Kahansim ML, Chaplin B, Imade G, Elujoba M, Paul M, Hamel DJ, Furuya H, Khouri R, Boaventura VS, de Moraes L, et al. Chikungunya virus antepartum transmission and abnormal infant outcomes in a cohort of pregnant women in Nigeria. Int J Infect Dis. 2024 Feb;139:92-100. doi: 10.1016/j.ijid.2023.11.036.
  18. 16.Aguilar Ticona JP, Xiao M, Li D, Nery N Jr, Hitchings M, Belitardo EMMA, Fofana MO, Victoriano R, Cruz JS, de Moraes L, et al. Extensive transmission of SARS-CoV-2 BQ.1* variant in a population with high levels of hybrid immunity: A prevalence survey. Int J Infect Dis. 2024 Feb;139:159-167. doi: 10.1016/j.ijid.2023.11.039.
  19. 15.Aguilar Ticona JP, Nery N Jr, Hitchings M, Belitardo EMMA, Fofana MO, Dorión M, Victoriano R, Cruz JS, Oliveira Santana J, de Moraes LEP, et al. Overestimation of Severe Acute Respiratory Syndrome Coronavirus 2 Household Transmission in Settings of High Community Transmission: Insights From an Informal Settlement Community in Salvador, Brazil. Open Forum Infect Dis. 2024 Feb 5;11(3):ofae065. doi: 10.1093/ofid/ofae065.
  20. 14.de Almeida Rego FF, de Moraes L, Giovanetti M, Silva JAG, Torres FG, de Oliveira Silva M, et al. Genomic Detection of the Emerging, Highly Pathogenic HIV-1 Subtype D in Bahia, Northeast Brazil. Viruses. 2023 Jul 29;15(8):1650. doi: 10.3390/v15081650.
  21. 13.Xavier J, Alcantara LCJ, Fonseca V, Lima M, Castro E, Fritsch H, Oliveira C, Guimarães N, Adelino T, Evaristo M, Rodrigues ES, Santos EV, de La-Roque D, de Moraes L, et al. Increased interregional virus exchange and nucleotide diversity outline the expansion of chikungunya virus in Brazil. Nat Commun. 2023 Jul 21;14(1):4413. doi: 10.1038/s41467-023-40099-y.
  22. 12.de Moraes L, Santos LA, Arruda LB, da Silva MDPP, Silva MO, Silva JAG, et al. High seroprevalence of Leishmania infantum is linked to immune activation in people with HIV: a two-stage cross-sectional study in Bahia, Brazil. Front Microbiol. 2023 Jul 19;14:1221682. doi: 10.3389/fmicb.2023.1221682.
  23. 11.de Moraes L, Portilho MM, Vrancken B, Van den Broeck F, Santos LA, Cucco M, et al. Analyses of Early ZIKV Genomes Are Consistent with Viral Spread from Northeast Brazil to the Americas. Viruses. 2023 May 25;15(6):1236. doi: 10.3390/v15061236.
  24. 10.Campos GS, Giovanetti M, Moraes L, Hora HSD, Bandeira ACA, Alcantara KVOM, et al. Genomic monitoring unveils a high prevalence of severe acute respiratory syndrome coronavirus 2 Omicron variant in vaccine breakthrough cases in Bahia, Brazil. Rev Assoc Med Bras. 2023 Mar 3;69(2):257-261. doi: 10.1590/1806-9282.20220955.
  25. 9.Giovanetti M, Pereira LA, Santiago GA, Fonseca V, Mendoza MPG, de Oliveira C, de Moraes L, et al. Emergence of Dengue Virus Serotype 2 Cosmopolitan Genotype, Brazil. Emerg Infect Dis. 2022 Aug;28(8):1725-1727. doi: 10.3201/eid2808.220550.
  26. 8.Martinez Viedma MDP, Panossian S, Gifford K, García K, Figueroa I, Parham L, de Moraes L, et al. Evaluation of ELISA-Based Multiplex Peptides for the Detection of Human Serum Antibodies Induced by Zika Virus Infection across Various Countries. Viruses. 2021 Jul 8;13(7):1319. doi: 10.3390/v13071319.
  27. 7.Peetluk LS, Rebeiro PF, Ridolfi FM, Andrade BB, Cordeiro-Santos M, Kritski A, Durovni B, Calvacante S, Figueiredo MC, Haas DW, Liu D, Rolla VC, Sterling TR; Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil Network. A Clinical Prediction Model for Unsuccessful Pulmonary Tuberculosis Treatment Outcomes. Clin Infect Dis. 2022 Mar 23;74(6):973-982. doi: 10.1093/cid/ciab598.
  28. 6.Cucco MS, de Moraes LEP, de Oliveira Andrade F, Khouri R, Galvão-Castro B, Araujo THA, et al. Molecular characterization of HTLV-1 genomic region hbz from patients with different clinical conditions. J Med Virol. 2021 Nov;93(11):6418-6423. doi: 10.1002/jmv.27005.
  29. 5.Machado Portilho M, de Moraes L, Kikuti M, Jacob Nascimento LC, Galvão Reis M, Sampaio Boaventura V, et al. Accuracy of the Zika IgM Antibody Capture Enzyme-Linked Immunosorbent Assay from the Centers for Disease Control and Prevention (CDC Zika MAC-ELISA) for Diagnosis of Zika Virus Infection. Diagnostics. 2020 Oct 18;10(10):835. doi: 10.3390/diagnostics10100835.
  30. 4.Akrami KM, de Nogueira BMF, do Rosário MS, de Moraes L, Cordeiro MT, Haddad R, et al. The re-emergence of Zika in Brazil in 2020: a case of Guillain Barré Syndrome during the low season for arboviral infections. J Travel Med. 2020 Nov 9;27(7):taaa165. doi: 10.1093/jtm/taaa165.
  31. 3.de Moraes L, Cerqueira-Silva T, Nobrega V, Akrami K, Santos LA, Orge C, et al. A clinical scoring system to predict long-term arthralgia in Chikungunya disease: A cohort study. PLoS Negl Trop Dis. 2020 Jul 21;14(7):e0008467. doi: 10.1371/journal.pntd.0008467.
  32. 2.Casais PM, Akrami K, Cerqueira-Silva T, Moraes LP, Rigaud VN, Neto ES, et al. Oral lesions are frequent in patients with Chikungunya infection. J Travel Med. 2020 Jul 14;27(4):taaa040. doi: 10.1093/jtm/taaa040.
  33. 1.Vinhaes ES, Santos LA, Dias L, Andrade NA, Bezerra VH, de Carvalho AT, de Moraes L, et al. Transient Hearing Loss in Adults Associated With Zika Virus Infection. Clin Infect Dis. 2017 Mar 1;64(5):675-677. doi: 10.1093/cid/ciw770.