Laise de Moraes

I'm

About

I have a background in handling NGS data analysis, from pre-processing and viral assembly to phylogenetic and phylodynamic analysis.

My current projects center on the molecular surveillance and diagnosis of (re)emerging arboviruses and respiratory viruses.

Skills

ILLUMINA TECHNOLOGY LIBRARY PREP
NANOPORE TECHNOLOGY LIBRARY PREP
SHELL SCRIPT
VIRAL GENOME ASSEMBLY
PHYLODINAMICS
R

Resume

Education

Ph.D Health Sciences

2018- 2024

Universidade Federal da Bahia, Bahia, Brazil

M.Sc. Health Sciences

2015 - 2017

Universidade Federal da Bahia, Bahia, Brazil

B.Sc. Biomedical Sciences

2010 - 2014

Escola Bahiana de Medicina e Saúde Pública, Bahia, Brazil

Professional Experience

Technical Fellow

2022 - Present

Plataforma de Vigilância Molecular, FIOCRUZ, IGM, Bahia, Brazil

Publications


2024

Aguilar Ticona JP, Nery N Jr, Hitchings M, Belitardo EMMA, Fofana MO, Dorión M, Victoriano R, Cruz JS, Oliveira Santana J, de Moraes LEP, Cardoso CW, Ribeiro GS, Reis MG, Khouri R, Costa F, Ko AI, Cummings DAT. Overestimation of Severe Acute Respiratory Syndrome Coronavirus 2 Household Transmission in Settings of High Community Transmission: Insights From an Informal Settlement Community in Salvador, Brazil. Open Forum Infect Dis. 2024 Feb 5;11(3):ofae065. doi: 10.1093/ofid/ofae065. PMID: 38516384
Sagay AS, Hsieh SC, Dai YC, Chang CA, Ogwuche J, Ige OO, Kahansim ML, Chaplin B, Imade G, Elujoba M, Paul M, Hamel DJ, Furuya H, Khouri R, Boaventura VS, de Moraes L, Kanki PJ, Wang WK. Chikungunya virus antepartum transmission and abnormal infant outcomes in a cohort of pregnant women in Nigeria. Int J Infect Dis. 2024 Feb;139:92-100. doi: 10.1016/j.ijid.2023.11.036. PMID: 38056689
Aguilar Ticona JP, Xiao M, Li D, Nery N Jr, Hitchings M, Belitardo EMMA, Fofana MO, Victoriano R, Cruz JS, de Moraes L, Strobel IM, Silva JJ, Sena do Aragão Filho A, Ribeiro GS, Reis MG, Costa F, Khouri R, Ko AI, Cummings DAT. Extensive transmission of SARS-CoV-2 BQ.1* variant in a population with high levels of hybrid immunity: A prevalence survey. Int J Infect Dis. 2024 Feb;139:159-167. doi: 10.1016/j.ijid.2023.11.039. PMID: 38070701

2023

de Almeida Rego FF, de Moraes L, Giovanetti M, Silva JAG, Torres FG, de Oliveira Silva M, da Purificação Pereira da Silva M, Van Weyenbergh J, Santos LA, Khouri R. Genomic Detection of the Emerging, Highly Pathogenic HIV-1 Subtype D in Bahia, Northeast Brazil. Viruses. 2023 Jul 29;15(8):1650. doi: 10.3390/v15081650. PMID: 37631993
Xavier J, Alcantara LCJ, Fonseca V, Lima M, Castro E, Fritsch H, Oliveira C, Guimarães N, Adelino T, Evaristo M, Rodrigues ES, Santos EV, de La-Roque D, de Moraes L, Tosta S, Neto A, Rosewell A, Mendonça AF, Leite A, Vasconcelos A, Silva de Mello AL, Vasconcelos B, Montalbano CA, Zanluca C, Freitas C, de Albuquerque CFC, Duarte Dos Santos CN, Santos CS, Dos Santos CA, Gonçalves CCM, Teixeira D, Neto DFL, Cabral D, de Oliveira EC, Noia Maciel EL, Pereira FM, Iani F, de Carvalho FP, Andrade G, Bezerra G, de Castro Lichs GG, Pereira GC, Barroso H, Franz HCF, Ferreira H, Gomes I, Riediger IN, Rodrigues I, de Siqueira IC, Silva J, Rico JM, Lima J, Abrantes J, do Nascimento JPM, Wasserheit JN, Pastor J, de Magalhães JJF, Luz KG, Lima Neto LG, Frutuoso LCV, da Silva LB, Sena L, de Sousa LAF, Pereira LA, Demarchi L, Câmara MCB, Astete MG, Almiron M, Lima M, Umaki Zardin MCS, Presibella MM, Falcão MB, Gale M Jr, Freire N, Marques N, de Moura NFO, Almeida Da Silva PE, Rabinowitz P, da Cunha RV, Trinta KS, do Carmo Said RF, Kato R, Stabeli R, de Jesus R, Hans Santos R, Kashima S, Slavov SN, Andrade T, Rocha T, Carneiro T, Nardy V, da Silva V, Carvalho WG, Van Voorhis WC, Araujo WN, de Filippis AMB, Giovanetti M. Increased interregional virus exchange and nucleotide diversity outline the expansion of chikungunya virus in Brazil. Nat Commun. 2023 Jul 21;14(1):4413. doi: 10.1038/s41467-023-40099-y. PMID: 37479700
de Moraes L, Santos LA, Arruda LB, da Silva MDPP, Silva MO, Silva JAG, Ramos A, Dos Santos MB, Torres FG, Orge C, Teixeira AMDS, Vieira TS, Ramírez L, Soto M, Grassi MFR, de Siqueira IC, Costa DL, Costa CHN, Andrade BB, Akrami K, de Oliveira CI, Boaventura VS, Barral-Netto M, Barral A, Vandamme AM, Van Weyenbergh J, Khouri R. High seroprevalence of Leishmania infantum is linked to immune activation in people with HIV: a two-stage cross-sectional study in Bahia, Brazil. Front Microbiol. 2023 Jul 19;14:1221682. doi: 10.3389/fmicb.2023.1221682. PMID: 37601355
de Moraes L, Portilho MM, Vrancken B, Van den Broeck F, Santos LA, Cucco M, Tauro LB, Kikuti M, Silva MMO, Campos GS, Reis MG, Barral A, Barral-Netto M, Boaventura VS, Vandamme AM, Theys K, Lemey P, Ribeiro GS, Khouri R. Analyses of Early ZIKV Genomes Are Consistent with Viral Spread from Northeast Brazil to the Americas. Viruses. 2023 May 25;15(6):1236. doi: 10.3390/v15061236. PMID: 37376536
Campos GS, Giovanetti M, Moraes L, Hora HSD, Bandeira ACA, Alcantara KVOM, Sardi SI. Genomic monitoring unveils a high prevalence of severe acute respiratory syndrome coronavirus 2 Omicron variant in vaccine breakthrough cases in Bahia, Brazil. Rev Assoc Med Bras. 2023 Mar 3;69(2):257-261. doi: 10.1590/1806-9282.20220955. PMID: 36888766

2022

Giovanetti M, Pereira LA, Santiago GA, Fonseca V, Mendoza MPG, de Oliveira C, de Moraes L, Xavier J, Tosta S, Fristch H, de Castro Barbosa E, Rodrigues ES, Figueroa-Romero D, Padilla-Rojas C, Cáceres-Rey O, Mendonça AF, de Bruycker Nogueira F, Venancio da Cunha R, de Filippis AMB, Freitas C, Peterka CRL, de Albuquerque CFC, Franco L, Méndez Rico JA, Muñoz-Jordán JL, Lemes da Silva V, Alcantara LCJ. Emergence of Dengue Virus Serotype 2 Cosmopolitan Genotype, Brazil. Emerg Infect Dis. 2022 Aug;28(8):1725-1727. doi: 10.3201/eid2808.220550. PMID: 35876608
Peetluk LS, Rebeiro PF, Ridolfi FM, Andrade BB, Cordeiro-Santos M, Kritski A, Durovni B, Calvacante S, Figueiredo MC, Haas DW, Liu D, Rolla VC, Sterling TR; Regional Prospective Observational Research in Tuberculosis (RePORT)-Brazil Network. A Clinical Prediction Model for Unsuccessful Pulmonary Tuberculosis Treatment Outcomes. Clin Infect Dis. 2022 Mar 23;74(6):973-982. doi: 10.1093/cid/ciab598. PMID: 34214166

2021

Martinez Viedma MdP, Panossian S, Gifford K, García K, Figueroa I, Parham L, de Moraes L, Nunes Gomes L, García-Salum T, Perret C, Weiskopf D, Tan GS, Augusto Silva A, Boaventura V, Ruiz-Palacios GM, Sette A, De Silva AD, Medina RA, Lorenzana I, Akrami KM, Khouri R, Olson D, Pickett BE. Evaluation of ELISA-Based Multiplex Peptides for the Detection of Human Serum Antibodies Induced by Zika Virus Infection across Various Countries. Viruses. 2021 Jul 8;13(7):1319. doi: 10.3390/v13071319. PMID: 34372525
Cucco MS, de Moraes LEP, de Oliveira Andrade F, Khouri R, Galvão-Castro B, Araujo TH, de Almeida Rego FF, Gois LL, Barreto FK, Santos LA. Molecular characterization of HTLV-1 genomic region hbz from patients with different clinical conditions. J Med Virol. 2021 Nov;93(11):6418-6423. doi: 10.1002/jmv.27005. Epub 2021 Jun 21. PMID: 33835501.

2020

Akrami KM, de Nogueira BMF, do Rosário MS, de Moraes L, Cordeiro MT, Haddad R, Gomes LN, de Pádua Carvalho I, Dos Reis Pimentel E, de Jesus Silva J, de Oliveira Francisco MVL, de Siqueira IC, Farias D, Barral-Netto M, Barral A, Boaventura V, Khouri R. The re-emergence of Zika in Brazil in 2020: a case of Guillain Barré Syndrome during the low season for arboviral infections. J Travel Med. 2020 Nov 9;27(7):taaa165. doi: 10.1093/jtm/taaa165. PMID: 32941627.
Machado Portilho M, de Moraes L, Kikuti M, Jacob Nascimento LC, Galvão Reis M, Sampaio Boaventura V, Khouri R, Sousa Ribeiro G. Accuracy of the Zika IgM Antibody Capture Enzyme-Linked Immunosorbent Assay from the Centers for Disease Control and Prevention (CDC Zika MAC-ELISA) for Diagnosis of Zika Virus Infection. Diagnostics (Basel). 2020 Oct 18;10(10):835. doi: 10.3390/diagnostics10100835. PMID: 33080935.
de Moraes L, Cerqueira-Silva T, Nobrega V, Akrami K, Santos LA, Orge C, Casais P, Cambui L, Rampazzo RCP, Trinta KS, Montalbano CA, Teixeira MJ, Cavalcante LP, Andrade BB, Cunha RVD, Krieger MA, Barral-Netto M, Barral A, Khouri R, Boaventura VS. A clinical scoring system to predict long-term arthralgia in Chikungunya disease: A cohort study. PLoS Negl Trop Dis. 2020 Jul 21;14(7):e0008467. doi: 10.1371/journal.pntd.0008467. eCollection 2020 Jul. PMID: 32693402.
Casais PM, Akrami K, Cerqueira-Silva T, Moraes LP, Rigaud VN, Neto ES, Orge CM, Gusmão LC, Cavalcanti LP, Santos LA, Barral-Netto M, Barral AP, Khouri R, Boaventura VS. Oral lesions are frequent in patients with Chikungunya infection. J Travel Med. 2020 Jul 14;27(4):taaa040. doi: 10.1093/jtm/taaa040. PMID: 32186714.
Penn-Nicholson A, Mbandi SK, Thompson E, Mendelsohn SC, Suliman S, Chegou NN, Malherbe ST, Darboe F, Erasmus M, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Winter J, Murphy M, Wood R, Morrow C, Van Rhijn I, Moody B, Murray M, Andrade BB, Sterling TR, Sutherland J, Naidoo K, Padayatchi N, Walzl G, Hatherill M, Zak D, Scriba TJ; Adolescent Cohort Study team; GC6-74 Consortium; SATVI Clinical and Laboratory Team; ScreenTB Consortium; AE-TBC Consortium; RePORT Brazil Team; Peruvian Household Contacts Cohort Team; CAPRISA IMPRESS team. RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response. Sci Rep. 2020 May 25;10(1):8629. doi: 10.1038/s41598-020-65043-8. PMID: 32451443.

2017

Vinhaes ES, Santos LA, Dias L, Andrade NA, Bezerra VH, de Carvalho AT, de Moraes L, Henriques DF, Azar SR, Vasilakis N, Ko AI, Andrade BB, Siqueira IC, Khouri R, Boaventura VS. Transient Hearing Loss in Adults Associated With Zika Virus Infection. Clin Infect Dis. 2017 Mar 1;64(5):675-677. doi: 10.1093/cid/ciw770. PMID: 27927858.

Contact


Location:

R. Waldemar Falcão, 121 - Candeal, Salvador - BA, 40296-710

Call:

+55 71 98689 6854

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